JP Journal of Biostatistics

The JP Journal of Biostatistics is a highly regarded open-access international journal indexed in the Emerging Sources Citation Index (ESCI). It focuses on the application of statistical theory and methods in resolving problems in biological, biomedical, and agricultural sciences. The journal encourages the submission of experimental papers that employ relevant algorithms and also welcomes survey articles in the fields of biostatistics and epidemiology.

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TRIGLYCERIDES AND HIGH-DENSITY LIPOPROTEIN (HDL): A NONPARAMETRIC REGRESSION APPROACH TO HEALTH ASSESSMENT

Authors

  • Faiza Awais
  • Wan Muhamad Amir W. Ahmad
  • Mohamad Nasarudin Adnan
  • Farah Muna Mohamad Ghazali
  • Nor Azlida Aleng

Keywords:

nonparametric regression, high density lipoprotein (HDL), triglycerides (TG)

DOI:

https://doi.org/10.17654/0973514325022

Abstract

This study develops a regression model that does not rely on specific parameters to evaluate high-density lipoprotein (HDL) levels, with triglycerides (TG) included as an important element. Considering the data's departure from typical patterns, this method provides strength in exploring intricate connections. The approach involves assessing multivariate normality, utilizing nonparametric regression modeling, and dividing the data into training and testing subsets. The Kendall-Theil-Sen-Siegel slope estimator is used to reduce the impact of outliers. Mardia's test indicates notable deviations from normality (skewness $=18.279, p=0.001$ ). The evaluation of the model shows impressive predictive performance with RMSE at 20.125 , mean absolute error (MAE) at 17.17, and median absolute error (MedAE) at 17.70. The final model, $\mathrm{HDL}=73.6+f(\mathrm{TG})$, offers a dependable framework for grasping TG's influence on HDL levels, enriching clinical insights, and guiding therapeutic choices.

Received: February 3, 2025
Accepted: March 21, 2025

References

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[6] R. Langrock, T. Adam, V. Leos-Barajas, S. Mews, D. L. Miller and Y. P. Papastamatiou, Spline-based nonparametric inference in general state-switching models, Statist. Neerlandica 72 (2018), 179-200.

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Published

2025-07-25

Issue

Vol. 25 No. 3 (2025)

Section

Articles

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How to Cite

TRIGLYCERIDES AND HIGH-DENSITY LIPOPROTEIN (HDL): A NONPARAMETRIC REGRESSION APPROACH TO HEALTH ASSESSMENT. (2025). JP Journal of Biostatistics, 25(3), 431-440. https://doi.org/10.17654/0973514325022

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